Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system
Liangliang Hao, Natalie Boehnke, Susanna K. Elledge, Nour-Saïda Harzallah, Renee T. Zhao, Eva Cai, Yu-Xiong Feng, Sofia Neaher, Heather E. Fleming, Piyush B. Gupta, Paula T. Hammond, and Sangeeta N. Bhatia
Inhalable point-of-care urinary diagnostic platform
QIAN ZHONG, EDWARD K. W. TAN, CARMEN MARTIN-ALONSO, TIZIANA PARISI, LIANGLIANG HAO, JESSE D. KIRKPATRICK, TAREK FADEL, HEATHER E. FLEMING, TYLER JACKS, AND SANGEETA N. BHATIA
CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics
Audrey E. Van Heest, Feiyang Deng, Renee T. Zhao, Nour Saida Harzallah, Heather E. Fleming, Sangeeta N. Bhatia, Liangliang Hao
Support strategies are needed for women in STEM with childcare responsibilities
Natalie Boehnke & Liangliang Hao
Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer
Maud-Emmanuelle Gilles, Liangliang Hao, Kaelyn Brown, Jihoon Lim, Sangeeta N Bhatia, Frank J Slack
iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer
Justin H. Lo*, Liangliang Hao*, Mandar D. Muzumdar, Srivatsan Raghavan, Ester J. Kwon, Emilia Pulver, Felicia Hsu, Andrew J. Aguirre, Brian M. Wolpin, Charles S. Fuchs, William C. Hahn, Tyler Jacks, Sangeeta N. Bhatia
Personalized RNA-medicine for pancreatic cancer
Maud-Emmanuelle Gilles, Liangliang Hao, Ling Huang, Rajesha Rupaimoole, Pedro P. Lopez-Casas, Emilia Pulver, Jong C. Jeong, Senthil K. Muthuswamy, Manuel Hidalgo, Sangeeta N. Bhatia and Frank J. Slack
Spherical nucleic acids as a divergent platform for synthesizing RNA-nanoparticle conjugates through enzymatic ligation
Jessica. L. Rouge, Liangliang Hao, Xiaochen. A. Wu, William E. Briley, Chad A. Mirkin
Biodegradable DNA-Brush Block Copolymer Spherical Nucleic Acids Enable Transfection Agent-Free Intracellular Gene Regulation
Chuan Zhang*, Liangliang Hao*, Colin M. Calabrese, Xiaochen A. Wu, Chad A. Mirkin
Antibody-Linked Spherical Nucleic Acids for Cellular Targeting
Ke Zhang*, Liangliang Hao*, Sarah J. Hurst, Chad A. Mirkin
Mechanism for the endocytosis of spherical nucleic acids nanoparticle conjugates
Chung Hang J. Choi*, Liangliang Hao*, Suguna P. Narayan, Evelyn Auyeung, Chad A. Mirkin
Spherical nucleic acid targeting microRNA-99b enhances intestinal MFG-E8gene expression and restores enterocyte migration in LPS-induced septic mice
Xiao Wang, Liangliang Hao, Heng-Fu Bu, Ke Tian, Fangyi Liu, Isabelle De Plaen, Yulan Liu, Chad A. Mirkin, and Xiao-Di Tan
miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma
Fotini M. Kouri, Lisa A. Hurley, Weston L. Daniel, Emily S. Day, Youjia Hua, Liangliang Hao, Chian-Yu Peng, Timothy J. Merkel, Markus A. Queisser, Carissa Ritner, Hailei Zhang, C. David James, Jacob I. Sznajder, Lynda Chin, David A. Giljohann, John A. Kessler, Marcus E. Peter, Chad A. Mirkin and Alexander H. Stegh.
Nucleic Acid–Gold Nanoparticle Conjugates as Mimics of microRNA
Liangliang Hao,Pinal C. Patel,Ali H. Alhasan,David A. Giljohann,Chad A. Mirkin
Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes
Nazanin Rohani, Liangliang Hao, Maria Alexis, Brian A. Joughin, Mira N. Moufarrej, Anthony Soltis, Shannon K. Hughes, Michael B. Yaffe, Douglas Lauffenburger, Christopher B. Burge, Sangeeta N. Bhatia, Frank Gertler
Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing
Natalie Boehnke*, Santiago Correa*, Liangliang Hao*, Wade Wang, Joelle P. Straehla, Sangeeta N. Bhatia, Paula T. Hammond (*Contributed equally)
Cancer cell-derived matrisome proteins promote metastasis in pancreatic ductal adenocarcinoma.
Chenxi Tian, Daniel Öhlund, Steffen Rickelt, Tommy Lidström, Ying Huang, Liangliang Hao, Renee T. Zhao, Oskar Franklin, Sangeeta N. Bhatia, David Tuveson, Richard Hynes
CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnostics
Liangliang Hao, Renee T. Zhao, Nicole L. Welch, Edward Kah Wei Tan, Qian Zhong, Nour Saida Harzallah, Chayanon Ngambenjawong, Henry Ko, Heather E. Fleming, Pardis C. Sabeti & Sangeeta N. Bhatia
Microenvironment-triggered multimodal precision diagnostics
Liangliang Hao, Nazanin Rohani, Renee T. Zhao, Emilia M. Pulver, Howard Mak, Olivia J. Kelada, Henry Ko, Heather E. Fleming, Frank B. Gertler & Sangeeta N. Bhatia